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清醒家兔压力感受性衰减的时间关系

Temporal relationships of barosensory attenuation in conscious rabbits.

作者信息

Gimpl M P, Brickman A L, Kaufman M P, Schneiderman N

出版信息

Am J Physiol. 1976 Jun;230(6):1480-6. doi: 10.1152/ajplegacy.1976.230.6.1480.

DOI:10.1152/ajplegacy.1976.230.6.1480
PMID:937536
Abstract

Electrical stimulation of anterior or posterior hypothalamus with 10-s trains elicited heart rate and blood pressure decreases. Presentation of anterior hypothalamic stimulation coincident with or 5, 10, or 15 s prior to 5-s train stimulation of aortic nerve (AN) summated with depressor-decelerator responses to AN stimulation. The summating effect was more pronounced for heart rate than for blood pressure. Simultaneous onset of AN and posterior hypothalamic stimulation did not influence AN responses. In contrast, when AN stimulation was delayed until 5, 10, or 15 s after onset of posterior hypothalamic stimulation, small, moderate, and full attenuation of AN responses occurred, respectively. Since AN and posterior hypothalamic stimulation each led to depressor-decelerator responses, attenuation of AN responses cannot be attributed to simple summation of cardiovascular responses elicited by intracranial and aortic nerve stimulation.

摘要

用10秒的串刺激下丘脑前部或后部会引起心率和血压下降。在对主动脉神经(AN)进行5秒串刺激之前5、10或15秒或与之同时进行下丘脑前部刺激,会与对AN刺激的降压-减速反应相加。心率的相加效应比对血压更明显。同时开始AN和下丘脑后部刺激不会影响AN反应。相反,当AN刺激延迟至下丘脑后部刺激开始后5、10或15秒时,AN反应分别出现小、中和完全衰减。由于AN和下丘脑后部刺激各自都会导致降压-减速反应,AN反应的衰减不能归因于颅内和主动脉神经刺激所引发的心血管反应的简单相加。

相似文献

1
Temporal relationships of barosensory attenuation in conscious rabbits.清醒家兔压力感受性衰减的时间关系
Am J Physiol. 1976 Jun;230(6):1480-6. doi: 10.1152/ajplegacy.1976.230.6.1480.
2
Posterior hypothalamic influences on cardiovascular effects of aortic nerve stimulation.下丘脑后部对主动脉神经刺激心血管效应的影响。
Am J Physiol. 1989 Dec;257(6 Pt 2):H1994-2000. doi: 10.1152/ajpheart.1989.257.6.H1994.
3
Barosensory neurons in the ventrolateral medulla in rabbits and their responses to various afferent inputs from peripheral and central sources.
Jpn J Physiol. 1986;36(6):1141-64. doi: 10.2170/jjphysiol.36.1141.
4
Cardiovascular responses elicited by hypothalamic stimulation in rabbits reveal a mediolateral organization.下丘脑刺激诱发的家兔心血管反应显示出一种内侧-外侧组织架构。
J Auton Nerv Syst. 1981 Nov;4(4):301-17. doi: 10.1016/0165-1838(81)90034-5.
5
Modulation of the baroreceptor reflex by stimulation of the hypothalamic defense and vigilance areas.通过刺激下丘脑防御和警觉区域对压力感受器反射进行调节。
Physiol Behav. 1996 Jun;59(6):1093-8. doi: 10.1016/0031-9384(95)02145-0.
6
[Discharges in the white rami communicantes evoked by stimulation of various sections of the hypothalamus].[下丘脑不同部位刺激诱发的白交通支放电]
Fiziol Zh SSSR Im I M Sechenova. 1978 Mar;64(3):263-70.
7
[Afferent projections of the aortic nerve onto different portions of the hypothalamic region].[主动脉神经向下丘脑区域不同部分的传入投射]
Biull Eksp Biol Med. 1977 Jun;83(6):643-6.
8
A GABAergic mechanism in the posterior hypothalamus modulates baroreflex bradycardia.下丘脑后部的一种γ-氨基丁酸能机制调节压力感受性反射性心动过缓。
Brain Res Bull. 1988 May;20(5):633-41. doi: 10.1016/0361-9230(88)90224-9.
9
[Action on cerebral electrogenesis and on blood pressure of the stimulation of the anterior or posterior hypothalamus in the conscious rabbit either adrenalectomized or not].[对清醒家兔(无论是否切除肾上腺)刺激下丘脑前部或后部对脑电发生及血压的作用]
Agressologie. 1975;16(2):79-83.
10
[The mechanisms of the influence of the anterior and posterior hypothalamus on the electrical activity of the large hemispheres of the forebrain and on autonomic reactions in hens].[下丘脑前部和后部对母鸡前脑大半球电活动及自主反应的影响机制]
Zh Evol Biokhim Fiziol. 1990 Mar-Apr;26(2):186-92.

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1
Respiratory and baroreceptor reflex interactions in man.人类呼吸与压力感受器反射的相互作用
J Clin Invest. 1977 May;59(5):780-5. doi: 10.1172/JCI108699.