Gugnani H C, Gugnani A, Malachy O
Department of Microbiology, University of Nigeria, Nsukka, Nigeria.
Mycoses. 1997 Sep;40(3-4):139-41. doi: 10.1111/j.1439-0507.1997.tb00203.x.
A 1% cream of sulconazole nitrate, an imidazole derivative, was used to treat 38 patients with diverse clinical types of dermatomycoses, including 16 cases of pityriasis versicolor, 14 of dermatophytosis (tinea pedis, tinea cruris, tinea corporis), two of balanoposthitis due to Candida albicans, another two of candidosis of the groin, one each of groin and foot infection due to Trichosporon beigelii and one case each of lesions of the hand and trunk caused by Petriellidium boydii and Scytalidium hyalinum respectively. A complete cure was achieved in 91% of patients, with resolution of the lesions in the majority within 2-4 weeks. There were only two relapses. Sulconazole is recommended as an effective drug for topical treatment of superficial fungal infections of the skin.
1%的硝酸硫康唑乳膏(一种咪唑衍生物)用于治疗38例不同临床类型的皮肤癣菌病患者,其中包括16例花斑癣、14例皮肤癣菌病(足癣、股癣、体癣)、2例白色念珠菌引起的龟头炎、另外2例腹股沟念珠菌病、1例由白吉利丝孢酵母引起的腹股沟和足部感染,以及分别由博伊德嗜皮菌和透明赛多孢引起的手部和躯干病变各1例。91%的患者实现了完全治愈,大多数患者的皮损在2至4周内消退。仅出现两例复发。硝酸硫康唑被推荐为治疗皮肤浅表真菌感染的有效外用药物。