Pincus T, Larsen A, Brooks R H, Kaye J, Nance E P, Callahan L F
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
J Rheumatol. 1997 Nov;24(11):2106-12.
To compare 3 quantitative hand radiograph scores, Steinbrocker stage, Larsen score, and Sharp score modified by Kaye, to one another and to other measures of clinical status in a cross sectional analysis of hand radiographs of 173 patients with rheumatoid arthritis (RA).
Radiographs were scored and compared to other measures of clinical status according to correlation and cross tabulation analyses.
In these cross sectional studies, radiographic scores according to all 3 methods were correlated at high levels (r(s) > 0.5) with one another and duration of disease, as well as with scores for physical joint deformity and limited motion; at lower levels (0.3 < r(s) < 0.5) with physical joint swelling scores, functional status, and age; and at low levels of marginal or no clinical importance (r(s) < 0.3) with physical joint tenderness scores, laboratory data, and pain scores.
The 3 scoring methods give similar quantitative information concerning hand radiographs of patients with RA. The Larsen and modified Sharp scores are preferred measures, as the detailed information facilitates comparison of different patients and monitoring of individual patients over time.
在一项对173例类风湿关节炎(RA)患者手部X线片的横断面分析中,比较3种手部X线片定量评分方法,即斯坦布鲁克分期、拉森评分以及经凯伊修改的夏普评分,相互之间以及与其他临床状态指标的差异。
根据相关性分析和交叉列表分析对X线片进行评分,并与其他临床状态指标进行比较。
在这些横断面研究中,所有3种方法的X线片评分彼此之间以及与病程、关节物理畸形评分和活动受限评分均高度相关(斯皮尔曼等级相关系数r(s)>0.5);与关节物理肿胀评分、功能状态评分和年龄中度相关(0.3<r(s)<0.5);与关节物理压痛评分、实验室数据和疼痛评分低度相关或临床重要性不大(r(s)<0.3)。
这3种评分方法在RA患者手部X线片方面提供了相似的定量信息。拉森评分和修改后的夏普评分是更优的测量方法,因为详细信息便于比较不同患者并随时间监测个体患者。