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[实验和临床条件下透析液的电化学再生]

[Electrochemical regeneration of dialysis solution in experimental and clinical conditions].

作者信息

Eventov V L, Andrianova M I, Maksimenko V A, Nefedkin S I, Ostodi T

机构信息

Scientific Center of Surgery RAMN, Moscow.

出版信息

Vestn Ross Akad Med Nauk. 1997(9):47-50.

PMID:9376743
Abstract

The authors have created a new system for electrochemical regeneration of dialysis solution and conducted 67 experiments using a model solution. Two groups of patients with terminal renal failure were treated. The regeneration system was applied in the treatment of Group 1 patients (n = 14), the traditional acetate hemodialysis procedure was used in Group 2 (n = 11). Hemodialysis with electrochemical regeneration of dialysis fluid removed creatinine and potassium ions from critically ill patients' blood as effectively as the traditional hemodialysis procedure. During electrochemical hemodialysis, middle-molecular toxins were removed better those with the traditional one, but urea and inorganic phosphorus were eliminated slowler. Electrochemical regeneration provided continuous purification of dialysis fluid. The regenerator block can be used many times. Sodium hypochlorite ensured self-sterilization of the system. The use of electrochemical regeneration does not require water purification, water communications and dialysis concentrate, which enables the detoxification procedure to be performed outside the specially equipped rooms.

摘要

作者创建了一种用于透析液电化学再生的新系统,并使用模型溶液进行了67次实验。对两组终末期肾衰竭患者进行了治疗。再生系统应用于第1组患者(n = 14)的治疗,第2组(n = 11)采用传统的醋酸盐血液透析程序。透析液电化学再生的血液透析从重症患者血液中清除肌酐和钾离子的效果与传统血液透析程序相同。在电化学血液透析过程中,中分子毒素的清除效果优于传统方法,但尿素和无机磷的清除速度较慢。电化学再生可实现透析液的连续净化。再生器模块可多次使用。次氯酸钠确保了系统的自我消毒。使用电化学再生不需要水净化、水连通和透析浓缩液,这使得解毒程序能够在特殊装备的房间之外进行。

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1
[Electrochemical regeneration of dialysis solution in experimental and clinical conditions].[实验和临床条件下透析液的电化学再生]
Vestn Ross Akad Med Nauk. 1997(9):47-50.
2
[Hemodialysis with electrochemical regeneration of dialysis solution].[采用透析液电化学再生的血液透析]
Anesteziol Reanimatol. 1995 Jul-Aug(4):70-1.
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Urol Nefrol (Mosk). 1995 Jul-Aug(4):25-7.
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Intradialytic changes of serum magnesium and their relation to hypotensive episodes in hemodialysis patients on different dialysates.不同透析液的血液透析患者透析期间血清镁的变化及其与低血压发作的关系。
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