Fisher M M
Anaesth Intensive Care. 1976 May;4(2):97-104. doi: 10.1177/0310057X7600400202.
In a series of patients who suffered severe histamine mediated reactions to induction agents and muscle relaxants, intradermal testing enabled the drug involved to be distinguished. The correct use of intradermal testing to give reliable results is discussed and a protocol described. Prausnitz Kustner testing was of little help in confirming the results. A number of patients tested showed high levels of immunoglobulin G (IgG) and it is believed that IgG mediated anaphylaxis may be the mechanism responsible for reactions that have been previously described as anaphylactoid or direct chemical histamine release.
在一系列对诱导剂和肌肉松弛剂发生严重组胺介导反应的患者中，皮内试验能够区分出所涉及的药物。本文讨论了正确使用皮内试验以获得可靠结果的方法，并描述了一个方案。普劳斯尼茨-屈斯特纳试验在证实结果方面帮助不大。一些接受检测的患者显示出高水平的免疫球蛋白G（IgG），据信IgG介导的过敏反应可能是先前被描述为类过敏反应或直接化学组胺释放的反应的发病机制。
