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硝苯地平在胃及十二指肠消化性溃疡中的应用

[The use of nifedipine in gastric and duodenal peptic ulcer].

作者信息

Oparin A G, Korenovskiĭ I P, Chonka V Iu, Fedchenko Iu G, Demerchan T I, Iakovenko E L

出版信息

Lik Sprava. 1996 May-Jun(5-6):123-5.

PMID:9377375
Abstract

It has been ascertained that use of nifedipine in antiulcer therapy is justified from the clinical standpoint as well as pathogenetically substantiated since its incorporation into the complex of therapeutic measures designed to treat patients with ulcer disease makes for a speedier cicatrization of ulcers as well as augmentation of the gastric mucose levels of periodic acid-Schiff reaction-positive substances and acid mucopolysaccharides, dispelling of hyperthermia foci, increase in bioelectric potentials and activation of motion of nuclei of epithelial cells of the pyloric portion of the stomach.

摘要

已经确定,从临床角度以及发病机制来看,硝苯地平用于抗溃疡治疗是合理的,因为将其纳入治疗溃疡病患者的综合治疗措施中,可使溃疡更快愈合,增加胃黏膜中过碘酸-希夫反应阳性物质和酸性粘多糖的水平,消除热病灶,提高生物电位并激活胃幽门部上皮细胞核的运动。

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