Thomsen H S, Levine E, Meilstrup J W, Van Slyke M A, Edgar K A, Barth J C, Hartman D S
Department of Diagnostic Radiology, Copenhagen University Hospital at Herlev, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Eur Radiol. 1997;7(8):1267-75. doi: 10.1007/s003300050288.
Renal cystic disease comprises a mixed group of heritable, developmental, and acquired disorders. Because of their diverse etiology, histology, and clinical presentation, no single scheme of classification has gained acceptance. Conditions include autosomal dominant polycystic kidney disease, acquired renal cystic disease, medullary sponge kidney, autosomal recessive polycystic kidney disease, multicystic dysplastic kidney, medullary cystic disease, tuberous sclerosis, cysts of the renal sinus, and von Hippel-Lindau's disease. An awareness of the pathology of each cystic disease is helpful in the understanding of the corresponding radiological images. Imaging techniques used in evaluating renal cystic disease include intravenous urography, sonography, CT, MRI, nuclear medicine, and renal angiography. Many types of cystic disease show similar imaging features. Meticulous attention to subtle radiological findings is therefore essential for reaching a correct diagnosis. Imaging features requiring analysis include whether the cysts are unilateral or bilateral, renal size and functional status, cyst distribution in the kidneys, and the presence of hemorrhagic and calcified renal cysts, solid renal masses, renal sinus cysts, and cysts in adjacent organs. Radiological findings should be carefully correlated with clinical features such as patient age, family history, symptoms, physical findings, and renal functional status before a diagnosis is attempted.
肾囊性疾病包括一组遗传性、发育性和后天性疾病的混合体。由于其病因、组织学和临床表现各不相同,目前尚无一种单一的分类方案得到广泛认可。这些疾病包括常染色体显性多囊肾病、获得性肾囊肿病、髓质海绵肾、常染色体隐性多囊肾病、多囊性发育不良肾、髓质囊肿病、结节性硬化症、肾窦囊肿以及冯·希佩尔-林道病。了解每种囊性疾病的病理学有助于理解相应的放射学影像。用于评估肾囊性疾病的成像技术包括静脉肾盂造影、超声检查、CT、MRI、核医学以及肾血管造影。许多类型的囊性疾病显示出相似的成像特征。因此,仔细关注细微的放射学表现对于做出正确诊断至关重要。需要分析的成像特征包括囊肿是单侧还是双侧、肾脏大小和功能状态、囊肿在肾脏内的分布以及出血性和钙化性肾囊肿、实性肾肿块、肾窦囊肿以及相邻器官囊肿的存在情况。在尝试做出诊断之前,应将放射学表现与临床特征(如患者年龄、家族史、症状、体格检查结果和肾功能状态)仔细关联起来。