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[纤维囊性乳腺病的某些方面]

[Some aspects of fibrocystic breast disease].

作者信息

Mizia-Stec K, Zych F

机构信息

II Katedry i Zakładu Patofizjologii Slaskiej Akademii Medycznej.

出版信息

Pol Merkur Lekarski. 1997 May;2(11):303-6.

PMID:9377675
Abstract

The fibro-cystic disease is very common disease. Hormonal factors: hyperestrogenemia, luteal deficiency, dysprolactinemia are inconstant. They are neither necessary nor sufficient to induce the cystic disease. The relations GCD (gross cystic disease) with breast cancer remain the fundamental problem. Although the cyst itself only exceptionally degenerates into cancer, the presence of macrocystic disease multiplies by 3 to 4 the risk of cancer. A lot of interesting examinations were performed on cyst fluids aspirated from patients to identify women with benign breast disease and particular risk for breast cancer. Electrolyte profiles showed, that cysts fluids may be divided into major subpopulations, which differ in terms of histological appearance of cyst lining epithelium and levels of other fluid constituents. At the present time, the biochemical measurements in cyst fluids aren't popular to identify women likely to develop breast cancer. We should use other diagnostic methods to examine these patients.

摘要

纤维囊性疾病是一种非常常见的疾病。激素因素:高雌激素血症、黄体功能不全、催乳素血症并不恒定。它们既不是诱发囊性疾病的必要条件,也不是充分条件。乳腺大囊性病(GCD)与乳腺癌的关系仍然是一个基本问题。虽然囊肿本身很少恶变为癌症,但大囊性病的存在会使患癌风险增加3至4倍。对从患者身上抽取的囊液进行了许多有趣的检查,以识别患有良性乳腺疾病且有乳腺癌特殊风险的女性。电解质分析表明,囊液可分为主要亚群,这些亚群在囊肿内衬上皮的组织学外观和其他液体成分水平方面存在差异。目前,囊液中的生化测量在识别可能患乳腺癌的女性方面并不常用。我们应该使用其他诊断方法来检查这些患者。

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