Arru G, Congiu A M, Burdino E, Ugazio G
Istituto di Biologia applicata e Genetica, Facoltà di Scienze M.F.N., Università di Sassari.
G Ital Med Lav Ergon. 1997 Jan-Mar;19(1):17-9.
The toxicity of Atrazine and that of its Desethylatrazine metabolite has been defined employing two organisms already tested in our labs the Dugesia gonocephala, belonging to a scissiparous strain coming from the island of Tavolara (Sardinia) and the Thamnocephalus platyurus, crustacean anostracan produced under form of quiescent cysts from Creasel Ltd. (Deinze, Belgium). It has been defined the lethal concentrations at 50% of Atrazine and of Desethylatrazine, of which it has been studied also the report dose-effect in the comparisons of the rectilinear motility. The results highlight that in the comparisons of the T. platyurus Atrazine expounds a toxicity of around three times that of its metabolite; this is not seen with the Planarians that are equally sensitive to both the compounds. The use of these two experimental models for the evaluation of the contamination of bodies of water is shown to be particularly useful given their great sensitivity to pollutants.
已使用我们实验室中已测试过的两种生物来确定阿特拉津及其去乙基阿特拉津代谢物的毒性,这两种生物分别是来自塔沃拉拉岛(撒丁岛)的裂体生殖品系的三角涡虫,以及由克雷塞尔有限公司(比利时代因泽)以静止囊肿形式生产的甲壳纲无甲目动物扁头鲎。已确定阿特拉津和去乙基阿特拉津的半数致死浓度,并在直线运动比较中研究了其剂量效应报告。结果表明,在扁头鲎的比较中,阿特拉津的毒性约为其代谢物的三倍;而涡虫对这两种化合物同样敏感,未出现这种情况。鉴于这两种实验模型对污染物具有高度敏感性,将它们用于评估水体污染特别有用。