Del Valle Núñez C J, García Guerrero M, García De Pesquera F, Pérez Bryan J
An Esp Pediatr. 1976 Mar-Apr;9(2):174-9.
L-dopa, administered at dose levels of 250 mg., was used to assess HGH release in 36 children. In five cases of hypopituitary dwarfs no response was obtained and in the remaining 31 cases affected by short stature not of endocrine origin, the highest peak was produced 30' after the test (12.71 +/- 11.61 ng/ml; p less than 0.0005). Significant responses were also obtained at 60' (11.81 +/- 10.47 ng/ml; p less than 0.0005), 90' (7.25 +/- 7.49 ng/ml; p less than 0.0005) and 120' (4.8 +/- 4.86 ng/ml; p less than 0.005).
以250毫克的剂量水平给予左旋多巴，用于评估36名儿童的生长激素释放情况。在5例垂体功能减退侏儒症患儿中未获得反应，其余31例非内分泌原因导致身材矮小的患儿，在试验后30分钟出现最高峰值（12.71±11.61纳克/毫升；p<0.0005）。在60分钟（11.81±10.47纳克/毫升；p<0.0005）、90分钟（7.25±7.49纳克/毫升；p<0.0005）和120分钟（4.8±4.86纳克/毫升；p<0.005）时也获得了显著反应。
