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局部应用盐酸环喷托酯的全身性不良反应。

Adverse systemic reactions of topical cyclopentolate hydrochloride.

作者信息

Awan K J

出版信息

Ann Ophthalmol. 1976 Jun;8(6):695-8.

PMID:937952
Abstract

Systemic toxic effects of 2% cyclopentolate eye drops were studied in 66 adults. Out of these, 10 developed systemic toxic reactions. In 6 cases it was mild and in the remaining 4 cases the severity was moderate. Recovery was complete without any treatment. It is suggested that the use of 2% cyclopentolate drops should be restricted, and weaker concentrations applied with caution.

摘要

对66名成年人研究了2%环喷托酯滴眼液的全身毒性作用。其中,10人出现全身毒性反应。6例为轻度,其余4例为中度。未经任何治疗即完全康复。建议限制使用2%环喷托酯滴眼液,并谨慎使用浓度较低的制剂。

相似文献

1
Adverse systemic reactions of topical cyclopentolate hydrochloride.局部应用盐酸环喷托酯的全身性不良反应。
Ann Ophthalmol. 1976 Jun;8(6):695-8.
2
Systemic toxicity of cyclopentolate hydrochloride in adults following topical ocular instillation.盐酸环喷托酯经眼部局部滴注后在成人中的全身毒性。
Ann Ophthalmol. 1976 Jul;8(7):803-6.
3
Systemic toxicity with cyclopentolate eye drop.环喷托酯滴眼液的全身毒性
J Indian Med Assoc. 1990 Sep;88(9):266.
4
Acute psychosis associated with topical cyclopentolate hydrochloride.与局部应用盐酸环喷托酯相关的急性精神病。
Am J Ophthalmol. 1988 Jan 15;105(1):91. doi: 10.1016/0002-9394(88)90128-6.
5
Myoclonic seizure due to cyclopentolate eye drop in a preterm infant.一名早产儿因使用环喷托酯滴眼液引发肌阵挛发作。
Turk J Pediatr. 2012 Jul-Aug;54(4):419-20.
6
Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions.盐酸环喷托酯可能的过敏反应:病例报告及用药与不良反应的文献综述
Ophthalmic Physiol Opt. 1991 Jan;11(1):16-21.
7
[Acute psychosis after cyclopentolate-HCL (Zyklolat) (author's transl)].
Klin Monbl Augenheilkd. 1979 Jul;175(1):100-2.
8
Comparison of the effect of atropine and cyclopentolate on myopia.阿托品与环喷托酯对近视影响的比较。
Ann Ophthalmol. 1989 May;21(5):180-2, 187.
9
Effect of combined 1% cyclopentolate-10% phenylephrine eye drops on systemic blood pressure of glaucoma patients.
Ann Ophthalmol. 1981 Jun;13(6):735-6.
10
Psychotic reaction in an adult after topical cyclopentolate.成人局部应用环喷托酯后出现的精神病性反应。
Ophthalmologica. 1980;181(3-4):228-30. doi: 10.1159/000309057.

引用本文的文献

1
Cycloplegic Refraction in Hyperopic Children: Effectiveness of a 0.5% Tropicamide and 0.5% Phenylephrine Addition to 1% Cyclopentolate Regimen.远视儿童的睫状肌麻痹验光:在1%环喷托酯方案中添加0.5%托吡卡胺和0.5%去氧肾上腺素的有效性
Korean J Ophthalmol. 2017 Jun;31(3):249-256. doi: 10.3341/kjo.2016.0007. Epub 2017 Apr 24.
2
[Intoxication with cyclopentolate eye drops].[环喷托酯滴眼液中毒]
Nervenarzt. 2009 Aug;80(8):967-9. doi: 10.1007/s00115-009-2790-5.
3
Plasma concentrations and ocular effects of cyclopentolate after ocular application of three formulations.
三种制剂眼部应用后环喷托酯的血浆浓度及眼部效应
Br J Clin Pharmacol. 1993 May;35(5):479-83. doi: 10.1111/j.1365-2125.1993.tb04173.x.