Stolk J, Versteegh M I, van der Peijl I D, Jaddoe V W
Afd. Longziekten, Universitair Medisch Centrum, Leiden.
Ned Tijdschr Geneeskd. 1997 Jul 5;141(27):1327-30.
Current drug treatment of pulmonary emphysema has little effect on quality of life and duration of survival. Surgical treatment for patients with severe pulmonary emphysema was recently introduced; it consists of resection of lung tissue with poor ventilation and perfusion. Surgical reduction of lung volume improves the forced expiratory pressure per second by 80-100% from 0.8 to 1.51. This increases the exercise tolerance and improves the patient's functioning in everyday life. The postoperative mortality and morbidity are acceptable.
目前肺气肿的药物治疗对生活质量和生存时长影响甚微。近期针对重度肺气肿患者引入了外科治疗;该治疗包括切除通气和灌注不良的肺组织。手术缩肺可使每秒用力呼气压力从0.8提升至1.51,提高80 - 100%。这增加了运动耐量并改善了患者的日常生活功能。术后死亡率和发病率在可接受范围内。