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[功能磁共振成像原理及其在大脑皮层激活研究中的可能性]

[Principles of functional MRI imaging and its possibilities in the study of cerebral cortex activation].

作者信息

Bogner P, Berényi E, Kövér G, Petrási Z, Repa I

机构信息

Diagnosztikai Központ, Pannon Agrártudományi Egyetem, Kaposvár.

出版信息

Orv Hetil. 1997 Sep 21;138(38):2391-5.

PMID:9380376
Abstract

While MR imaging of anatomic structures has long been widely appreciated, the emergence of functional magnetic resonance imaging (FMRI) methods for localising brain activity has emerged in the beginning of the 90s. This new MRI technique produces images of activated brain regions by detecting the indirect effects of neural activity on local blood volume, flow and oxygen saturation, and it is a promising new tool for further understanding of the relationships among brain structure, function and pathology. The information revealed by FMRI is partially overlapping with PET and SPECT, but it is non-invasive and has a better spatial and temporal resolution. The authors briefly summarise the concept and basics of FMRI and demonstrate the first successful FMRI examination performed in Hungary. The potential role of FMRI in the clinical practice is presented.

摘要

虽然解剖结构的磁共振成像早已得到广泛认可,但用于定位脑活动的功能磁共振成像(FMRI)方法在20世纪90年代初才出现。这种新的磁共振成像技术通过检测神经活动对局部血容量、血流和氧饱和度的间接影响来生成激活脑区的图像,它是进一步理解脑结构、功能和病理学之间关系的一种有前景的新工具。FMRI揭示的信息与正电子发射断层扫描(PET)和单光子发射计算机断层扫描(SPECT)部分重叠,但它是非侵入性的,并且具有更好的空间和时间分辨率。作者简要总结了FMRI的概念和基础,并展示了在匈牙利进行的首次成功的FMRI检查。还介绍了FMRI在临床实践中的潜在作用。

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