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[使用个人积分法测试组织对手术缝线的反应性]

[Testing tissue reactivity to surgical sutures using a personal point method].

作者信息

Staniszewska-Kuś J, Rutowski R, Paluch D

机构信息

Zakład Chirurgii Eksperymentalnej i Badania Biomateriałow, Katedra Chirurgii Urazowej Akademii Medycznej we Wrocławiu.

出版信息

Polim Med. 1997;27(1-2):3-15.

PMID:9380600
Abstract

In the Institution of Experimental and Biomaterial Research Surgery of Medical Academy in Wrocław works on biological methods of estimation of different biomaterials including, first of all, surgical threads have been carried out for 30 years. The purpose of this work is to define the local biological reaction on the implanted absorptive and non-absorptive surgical threads. The present estimation of reactivity of surgical threads depended on a description of a great number of histological samples and on observation of numerous microscopic fields for each tested thread. It required long and tiring descriptions the analysis of which was made difficult and often led to non-objective conclusions. The presented punctual system depends on observation of the field of vision in a biological microscope which includes transverse cross-section of the implanted thread together with the surrounding tissues. The estimation of the histological samples in magnification of 45 times allows to define the range of infiltration of tissues with inflammatory cells in comparison with the diameter of the implanted thread. Observations in magnification 120 times allow to differentiate cells included in non-specific inflammatory process. The worked put punctual system enables to define the level of tissue reaction on the basis of uniform criteria.

摘要

在弗罗茨瓦夫医学院实验与生物材料研究外科机构,针对包括外科缝线在内的不同生物材料的生物学评估方法的研究已开展了30年。这项工作的目的是确定植入的可吸收和不可吸收外科缝线的局部生物反应。目前对外科缝线反应性的评估依赖于对大量组织学样本的描述以及对每根测试缝线众多微观视野的观察。这需要冗长且累人的描述,其分析变得困难,并且常常导致非客观的结论。所提出的评分系统依赖于在生物显微镜下对视野的观察,该视野包括植入缝线的横截面及其周围组织。在45倍放大倍数下对组织学样本的评估能够确定与植入缝线直径相比炎症细胞对组织的浸润范围。在120倍放大倍数下的观察能够区分非特异性炎症过程中包含的细胞。所开展的评分系统能够基于统一标准确定组织反应的程度。

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