Ayala-Gaytán J J, Condarco-Cortés B A, Pérez-Zuno J A, Moreno-Guevara P
Servicios de Infectología, Instituto Mexicano del Seguro Social, Monterrey, N.L.
Rev Invest Clin. 1997 May-Jun;49(3):205-8.
We report our experience with ten virgin cases (5 children, 5 adults) with coccidioidal meningitis treated with fluconazole. The diagnosis was confirmed by a positive culture of the cerebrospinal fluid. Fluconazole at doses of 6/mg/kg/day for children and 400 mg/day for adults were given. All responded well, in five it was discontinued and four relapsed but responded well to fluconazole. We conclude that fluconazole is useful for coccidioidal meningitis.
我们报告了10例初治球孢子菌性脑膜炎患者(5名儿童,5名成人)接受氟康唑治疗的经验。脑脊液培养阳性确诊了该诊断。儿童给予氟康唑剂量为6mg/kg/天,成人给予400mg/天。所有患者反应良好,5例停药,4例复发但对氟康唑反应良好。我们得出结论,氟康唑对球孢子菌性脑膜炎有用。