Crayton J W, Meltzer H Y
Arch Gen Psychiatry. 1976 Jun;33(6):679-81. doi: 10.1001/archpsyc.1976.01770060021003.
Serum creatine phosphokinase (CPK) activity was determined in a series of 101 sequential admissions to the Pritzker Children's Hospital, an inpatient psychiatric facility. Black children had significantly higher serum CPK levels than whites, and males had significantly higher levels than females, as is the case with adults. There was a higher incidence of CPK elevations in children with organic brain pathology than in children with personality disorders or schizoprenia. Children with chronic symptoms of a psychotic nature did not have increased serum CPK activity, which is similar to the findings in adults. There were no children in the sample with acute psychotic symptoms, so it was not possible to determine whether acute psychosis in children is accompanied by increased serum CPK activity, as it frequently is in psychotics over the age of 17.
对普里茨克儿童医院（一家住院精神科机构）连续收治的101名患儿测定了血清肌酸磷酸激酶（CPK）活性。黑人儿童的血清CPK水平显著高于白人儿童，男性儿童的CPK水平显著高于女性儿童，成人情况也如此。患有器质性脑病变的儿童CPK升高的发生率高于患有个性障碍或精神分裂症的儿童。有慢性精神病性症状的儿童血清CPK活性并未升高，这与成人的研究结果相似。样本中没有患有急性精神病性症状的儿童，因此无法确定儿童急性精神病是否像17岁以上精神病患者那样伴有血清CPK活性升高。
