糖蛋白IIb/IIIa血小板受体阻滞剂替罗非班而非肝素可对抗不稳定型心绞痛中的血小板聚集。
The glycoprotein IIb/IIIa platelet receptor blocker tirofiban, but not heparin, counteracts platelet aggregation in unstable angina pectoris.
作者信息
Mattsson E, Martinsson A, Nyqvist O, Rasmanis G, Sylvén C, Karlberg K E
机构信息
Karolinska Institute at Department of Cardiology, Huddinge University Hospital, Sweden.
出版信息
Am J Cardiol. 1997 Oct 1;80(7):938-40. doi: 10.1016/s0002-9149(97)00549-3.
PMID:9382012
Abstract
In this study, despite concomitant aspirin treatment, tirofiban, but not heparin, reduced platelet aggregation in patients with acute myocardial ischemia. Platelet aggregation was determined with 2 independent methods, filtragometry and whole blood aggregometry.
摘要
在本研究中，尽管同时进行了阿司匹林治疗，但替罗非班而非肝素降低了急性心肌缺血患者的血小板聚集。采用两种独立方法（滤过法和全血凝集法）测定血小板聚集。
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