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氰酸盐诱发的镰状细胞血红蛋白病患者白内障

Cyanate-induced cataracts in patients with sickle-cell hemoglobinopathies.

作者信息

Nicholson D H, Harkness D R, Benson W E, Peterson C M

出版信息

Arch Ophthalmol. 1976 Jun;94(6):927-30. doi: 10.1001/archopht.1976.03910030465005.

DOI:10.1001/archopht.1976.03910030465005
PMID:938283
Abstract

Two young patients developed bilateral posterior subcapsular cataracts while receiving oral sodium cyanate for treatment of sickle cell hemoglobinopathy. In one of the patients, lens opacities regressed spontaneously after cyanate therapy was discontinued.

摘要

两名年轻患者在接受口服氰酸钠治疗镰状细胞血红蛋白病时出现双侧后囊下白内障。其中一名患者在停用氰酸盐治疗后晶状体混浊自发消退。

相似文献

1
Cyanate-induced cataracts in patients with sickle-cell hemoglobinopathies.氰酸盐诱发的镰状细胞血红蛋白病患者白内障
Arch Ophthalmol. 1976 Jun;94(6):927-30. doi: 10.1001/archopht.1976.03910030465005.
2
Clinical evaluation of cyanate in sickle cell anemia.镰状细胞贫血中氰酸盐的临床评估。
Prog Hematol. 1975;9:157-84.
3
Sodium cyanate as a potential treatment for sickle-cell disease.氰酸钠作为镰状细胞病的一种潜在治疗方法。
N Engl J Med. 1974 Mar 21;290(12):654-60. doi: 10.1056/NEJM197403212901204.
4
Sodium cyanate-induced ocular lesions in the beagle.氰酸钠诱导比格犬眼部病变。
J Pharmacol Exp Ther. 1977 Jan;200(1):10-6.
5
Sodium cyanate induced polyneuropathy in patients with sickle-cell disease.氰酸钠可诱发镰状细胞病患者发生多发性神经病。
Ann Intern Med. 1974 Aug;81(2):152-8. doi: 10.7326/0003-4819-81-2-152.
6
Preliminary studies of continuous extracorporeal carbamylation in the treatment of sickle cell anemia.连续体外氨甲酰化治疗镰状细胞贫血的初步研究。
J Lab Clin Med. 1982 Sep;100(3):345-55.
7
Therapy of sickle cell disease: an approach with sodium cyanate.镰状细胞病的治疗:氰酸钠疗法
Semin Hematol. 1974 Oct;11(4):569-76.
8
Studies with intravenous sodium cyanate in patients with sickle cell anemia.镰状细胞贫血患者静脉注射氰酸钠的研究。
J Pharmacol Exp Ther. 1974 Jun;189(3):577-84.
9
The clinical use of cyanate in sickling.
N Engl J Med. 1972 Jul 13;287(2):98-100. doi: 10.1056/NEJM197207132870210.
10
Increased survival of sickle-cell erythrocytes after treatment in vitro with sodium cyanate.用氰酸钠体外处理后镰状细胞红细胞的存活率增加。
Proc Natl Acad Sci U S A. 1971 Nov;68(11):2791-3. doi: 10.1073/pnas.68.11.2791.

引用本文的文献

1
Phage-Display-Derived Peptide Specific to Carbamylated Protein.对氨甲酰化蛋白具有特异性的噬菌体展示衍生肽
ACS Omega. 2021 Jan 25;6(4):3079-3089. doi: 10.1021/acsomega.0c05481. eCollection 2021 Feb 2.
2
Protein carbamylation is a hallmark of aging.蛋白质氨甲酰化是衰老的一个标志。
Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1191-6. doi: 10.1073/pnas.1517096113. Epub 2015 Dec 28.
3
Protein carbamylation in kidney disease: pathogenesis and clinical implications.肾脏疾病中的蛋白质氨甲酰化:发病机制及临床意义
Am J Kidney Dis. 2014 Nov;64(5):793-803. doi: 10.1053/j.ajkd.2014.04.034. Epub 2014 Jul 16.
4
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
J Protein Chem. 1995 Apr;14(3):179-88. doi: 10.1007/BF01980330.
5
Formation of covalent adducts between cortisol and 16 alpha-hydroxyestrone and protein: possible role in the pathogenesis of cortisol toxicity and systemic lupus erythematosus.皮质醇与16α-羟基雌酮及蛋白质之间共价加合物的形成:在皮质醇毒性和系统性红斑狼疮发病机制中的可能作用。
Proc Natl Acad Sci U S A. 1982 May;79(10):3320-4. doi: 10.1073/pnas.79.10.3320.
6
Conformational changes induced in bovine lens alpha-crystallin by carbamylation. Relevance to cataract.
Biochem J. 1984 Oct 1;223(1):221-7. doi: 10.1042/bj2230221.
7
A case-control study of cataract in Oxfordshire: some risk factors.牛津郡白内障病例对照研究:一些危险因素
Br J Ophthalmol. 1988 Nov;72(11):804-8. doi: 10.1136/bjo.72.11.804.
8
Site of carbamoylation of bovine gamma-II-crystallin by potassium [14C]cyanate.[14C]氰酸钾对牛γ-II-晶状体蛋白的氨甲酰化位点。
Biochem J. 1989 Sep 15;262(3):909-15. doi: 10.1042/bj2620909.