Franck H, Munz M, Scherrer M
Clinic Mayenbad, Badstr. 14, 88339 Bad Waldsee, Germany.
Calcif Tissue Int. 1997 Dec;61(6):445-7. doi: 10.1007/s002239900365.
Bone densitometry focuses on bone mineral area density (BMD in g/cm2) of the proximal femur and spine in anterior-posterior (AP) projections. Artifacts, such as osteoarthritis and osteophytic calcifications (OC) influence spine BMD, especially in AP scans. If only two sites are measured, as is usual in clinical practice, there may be advantages to measuring both femora rather than one femur and the spine. This would not be useful, however, if there was strong symmetry between the two sides. Furthermore, fan beam (FB) techniques have become available for measuring BMD with less data acquisition time. We compared densitometry of opposing femora in 421 patients (369 women, mean age 59.0 +/- 4.8; 52 men, mean age 56.9 +/- 7.4) using dual-energy X-ray absorptiometry (DXA): both single-beam (SB) and FB modes were evaluated. The precision errors in vivo (short- and midterm) of total BMD were 0.7% for both SB and FB. The total BMD and BMC of the left hip (0.817 +/- 0.124 g/cm2, 31. 3 +/- 6.4 g) were significantly (P < 0.001) higher (2-3%) than the corresponding values of the right hip (0.801 +/- 0.125 g/cm2, 30.3 +/- 6.3 g) in both SB and FB (left BMD 0.802 +/- 0.117 g/cm2, BMC 30. 0 +/- 6.2 g versus right BMD 0.795 +/- 0.117 g/cm2, BMC 29.3 +/- 6.3 g) modes. However, BMD of the femoral neck and Ward's triangle were not significantly (P > 0.05) different between the two sides. The FB results were generally 2% lower than SB results. There were highly significant (P < 0.001) correlations (r > 0.9) between both hips using both SB and FB. For diagnostic procedures and longitudinal studies, one should consider that there are bilateral differences of femur BMD, as well as differences between FB and SB scan modes.
骨密度测定主要关注前后位(AP)投照下股骨近端和脊柱的骨矿物质面积密度(BMD,单位为g/cm²)。诸如骨关节炎和骨赘钙化(OC)等伪影会影响脊柱BMD,尤其是在AP扫描中。如果像临床实践中通常那样仅测量两个部位,那么测量双侧股骨而非一侧股骨和脊柱可能有优势。然而,如果两侧存在很强的对称性,这样做就没有意义了。此外,扇形束(FB)技术已可用于以更短的数据采集时间测量BMD。我们使用双能X线吸收法(DXA)比较了421例患者(369名女性,平均年龄59.0±4.8岁;52名男性,平均年龄56.9±7.4岁)双侧股骨的骨密度:对单束(SB)和FB模式均进行了评估。SB和FB模式下体内(短期和中期)总BMD的精确误差均为0.7%。在SB和FB模式下,左髋的总BMD和骨矿含量(BMC)(分别为0.817±0.124 g/cm²,31.3±6.4 g)均显著高于右髋相应值(分别为0.801±0.125 g/cm²,30.3±6.3 g)(P<0.001)(左BMD 0.802±0.117 g/cm²,BMC 30.0±6.2 g;右BMD 0.795±0.117 g/cm²,BMC 29.3±6.3 g)。然而,两侧股骨颈和沃德三角区的BMD差异无统计学意义(P>0.05)。FB结果总体上比SB结果低2%。使用SB和FB模式时,双侧髋部之间均存在高度显著的相关性(P<0.001,r>0.9)。对于诊断程序和纵向研究,应考虑到股骨BMD存在双侧差异,以及FB和SB扫描模式之间的差异。