Janmey P A
Brigham and Women's Hospital, Department of Biomedical and Biological Sciences, Harvard Medical School, Boston, MA 02115, USA.
Chem Biol. 1995 Feb;2(2):61-5. doi: 10.1016/1074-5521(95)90276-7.
Phosphatidylinositol lipids are best known as a source of the second messengers inositol trisphosphate and diacylglycerol. Some phosphatidylinositol lipids may directly regulate cytoskeletal events, however. To understand the role of lipids in signaling, help from both synthetic chemists and physical chemists is needed.
磷脂酰肌醇脂质作为第二信使三磷酸肌醇和二酰基甘油的来源最为人所知。然而，一些磷脂酰肌醇脂质可能直接调节细胞骨架事件。为了理解脂质在信号传导中的作用，需要合成化学家和物理化学家的帮助。
