Bovine nasal granuloma in Victoria -- a search for the causative allergens.

Cows with nasal granuloma showed skin sensitivity to a range of environmental allergens while clinically normal control animals showed little sensitivity. The allergens producing the greatest number of positive reactions included the pollens of dock, capeweed, clover, paspalum, sorrel, rye grass, pepper tree and wattle, the spores of penicillium, cladosporium, botrytis and rye grass rust and extracts of sheep's wool and mite. It is likely that different allergens are important in different animals and in different regions and their importance in the aetiology of nasal granuloma probably depends on their presence in the inhaled air in high concentration for long periods.