Coutinho R, David R J, Collins J W
Cook County Children's Hospital, and Department of Pediatrics, School of Medicine, University of Illinois at Chicago, USA.
Am J Epidemiol. 1997 Nov 15;146(10):804-9. doi: 10.1093/oxfordjournals.aje.a009197.
The authors used a transgenerational data set of Illinois vital records to ascertain the relation between parental birth weights and infant birth weight. The infant generation consisted of all African Americans and whites born in Illinois during 1989-1991. The parent generation included the mothers and fathers who were also born in Illinois between 1956 and 1975. In the infant cohort, the rate of low birth weight (LBW) (<2,500 g) was 11.7% for African Americans (n = 15,287) versus 5.0% for whites (n = 117,708) (relative risk (RR) = 2.3, 95% confidence interval (CI) 2.2-2.5). For African Americans, the LBW rate was 17.9% among those born to LBW mothers (n = 1,943) compared with 10.8% among those born to non-LBW mothers (n = 13,344) (RR = 1.8, 95% CI 1.6-1.9). For whites, the LBW rate was 8.5% among those born to LBW mothers (n = 2,174) compared with 4.8% among those born to non-LBW mothers (n = 115,534) (RR = 1.7, 95% CI 1.6-2.0). A weaker association was observed between paternal birth weight and infant birth weight. The authors conclude that parental birth weights are important risk factors for LBW in both African Americans and whites.
作者使用了伊利诺伊州生命记录的跨代数据集来确定父母出生体重与婴儿出生体重之间的关系。婴儿一代包括1989年至1991年在伊利诺伊州出生的所有非裔美国人和白人。父母一代包括1956年至1975年也在伊利诺伊州出生的母亲和父亲。在婴儿队列中，非裔美国人（n = 15287）的低出生体重（LBW）（<2500克）率为11.7%，而白人（n = 117708）为5.0%（相对风险（RR）= 2.3，95%置信区间（CI）2.2 - 2.5）。对于非裔美国人，低出生体重母亲所生婴儿的低出生体重率为17.9%（n = 1943），而非低出生体重母亲所生婴儿的低出生体重率为10.8%（n = 13344）（RR = 1.8，95% CI 1.6 - 1.9）。对于白人，低出生体重母亲所生婴儿的低出生体重率为8.5%（n = 2,174），而非低出生体重母亲所生婴儿的低出生体重率为4.8%（n = 115534）（RR = 1.7，95% CI 1.6 - 2.0）。观察到父亲出生体重与婴儿出生体重之间的关联较弱。作者得出结论，父母出生体重是非裔美国人和白人低出生体重的重要风险因素。
