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通过表位作图分析研究牙龈卟啉单胞菌菌株及其他厌氧菌中菌毛和血凝黏附素HA-Ag2的保守性。

Conservation of fimbriae and the hemagglutinating adhesin HA-Ag2 among Porphyromonas gingivalis strains and other anaerobic bacteria studied by epitope mapping analysis.

作者信息

Du L, Pellen-Mussi P, Chandad F, Mouton C, Bonnaure-Mallet M

机构信息

Equipe de Biologie Buccale UPRES EA 1256, UFR Odontologie, Université de Rennes I, France.

出版信息

Clin Diagn Lab Immunol. 1997 Nov;4(6):711-4. doi: 10.1128/cdli.4.6.711-714.1997.

DOI:10.1128/cdli.4.6.711-714.1997
PMID:9384294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC170645/
Abstract

Monoclonal antibodies characterized as antifimbria and anti-HA-Ag2 were used in immunoblotting to examine the antigenic distribution of fimbriae and HA-Ag2 among a collection of human and animal Porphyromonas strains and human Prevotella and Bacteroides strains. The results showed that fimbrial and HA-Ag2 antigenic structures are peculiar to the species Porphyromonas gingivalis.

摘要

被鉴定为抗菌毛和抗HA-Ag2的单克隆抗体用于免疫印迹，以检测菌毛和HA-Ag2在一系列人和动物牙龈卟啉单胞菌菌株以及人普雷沃菌属和拟杆菌属菌株中的抗原分布。结果表明，菌毛和HA-Ag2抗原结构是牙龈卟啉单胞菌所特有的。

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Characterization of recombinant and native forms of a cell surface antigen of Porphyromonas (Bacteroides) gingivalis.牙龈卟啉单胞菌（拟杆菌属）细胞表面抗原重组形式和天然形式的特性分析
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Proteins with molecular masses of 50 and 80 kilodaltons encoded by genes downstream from the fimbrilin gene (fimA) are components associated with fimbriae in the oral anaerobe Porphyromonas gingivalis.由菌毛蛋白基因（fimA）下游基因编码的分子量为50和80千道尔顿的蛋白质是口腔厌氧菌牙龈卟啉单胞菌中与菌毛相关的成分。
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Antigenic, structural, and functional relationships between fimbriae and the hemagglutinating adhesin HA-Ag2 of Porphyromonas gingivalis.牙龈卟啉单胞菌菌毛与血凝黏附素HA-Ag2之间的抗原、结构及功能关系
Infect Immun. 1995 Dec;63(12):4755-63. doi: 10.1128/iai.63.12.4755-4763.1995.