通过表位作图分析研究牙龈卟啉单胞菌菌株及其他厌氧菌中菌毛和血凝黏附素HA-Ag2的保守性。
Conservation of fimbriae and the hemagglutinating adhesin HA-Ag2 among Porphyromonas gingivalis strains and other anaerobic bacteria studied by epitope mapping analysis.
作者信息
Du L, Pellen-Mussi P, Chandad F, Mouton C, Bonnaure-Mallet M
机构信息
Equipe de Biologie Buccale UPRES EA 1256, UFR Odontologie, Université de Rennes I, France.
出版信息
Clin Diagn Lab Immunol. 1997 Nov;4(6):711-4. doi: 10.1128/cdli.4.6.711-714.1997.
Abstract
Monoclonal antibodies characterized as antifimbria and anti-HA-Ag2 were used in immunoblotting to examine the antigenic distribution of fimbriae and HA-Ag2 among a collection of human and animal Porphyromonas strains and human Prevotella and Bacteroides strains. The results showed that fimbrial and HA-Ag2 antigenic structures are peculiar to the species Porphyromonas gingivalis.
摘要
被鉴定为抗菌毛和抗HA-Ag2的单克隆抗体用于免疫印迹，以检测菌毛和HA-Ag2在一系列人和动物牙龈卟啉单胞菌菌株以及人普雷沃菌属和拟杆菌属菌株中的抗原分布。结果表明，菌毛和HA-Ag2抗原结构是牙龈卟啉单胞菌所特有的。
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