Piven J
Department of Psychiatry, University of Iowa College of Medicine, Psychiatry Research, Medical Education Building, Room 1-293, Iowa City, Iowa 52242, USA.
Curr Opin Neurobiol. 1997 Oct;7(5):708-12. doi: 10.1016/s0959-4388(97)80093-1.
Stimulated by recent advances in genetics and neurobiology, there has been a rapid expansion of studies aimed at elucidating the biological basis of autism. Molecular genetic studies looking for susceptibility genes in this disorder are currently being conducted, and neuroimaging studies attempting to identify characteristic structural and functional brain abnormalities are under way. The results of these studies are likely to have a significant impact on our understanding of the pathogenesis of autism.
受遗传学和神经生物学近期进展的刺激，旨在阐明自闭症生物学基础的研究迅速增加。目前正在进行寻找该疾病易感基因的分子遗传学研究，同时也在开展试图识别大脑特征性结构和功能异常的神经影像学研究。这些研究结果可能会对我们理解自闭症的发病机制产生重大影响。
