Kim S, Haas G P, Hillman G G
Department of Urology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Cytokines Mol Ther. 1996 Mar;2(1):13-9.
The key to understanding cancer has eluded scientists for years. As we discover new and more effective approaches to the treatment of cancer, the more we have yet to explore. Despite landmark advances in molecular biology and surgical adjuvant therapy in the past decade, cancer remains a significant life threat. Most metastatic cancers are refractory to conventional therapies, including surgery, radiation therapy and chemotherapy. Therefore constant efforts are being made to develop more effective treatment modalities. Immunotherapy, which is based on the enhancement of an immune response against the host tumor, has been particularly promising. In this review, we shall address the origins, development and future directions of immunotherapy.
多年来，理解癌症的关键一直让科学家们捉摸不透。随着我们发现越来越多治疗癌症的新方法且这些方法愈发有效，我们有待探索的领域也越来越多。尽管在过去十年分子生物学和手术辅助治疗取得了具有里程碑意义的进展，但癌症仍然严重威胁着生命。大多数转移性癌症对包括手术、放疗和化疗在内的传统疗法具有抗性。因此，人们一直在不断努力开发更有效的治疗方式。基于增强针对宿主肿瘤的免疫反应的免疫疗法一直特别有前景。在这篇综述中，我们将探讨免疫疗法的起源、发展和未来方向。
