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The effects of imidazoacridinones, new antineoplastic agents, on the human erythrocyte membrane.

作者信息

Jóźwiak Z, Pacholska M, Szwarocka A

机构信息

Department of Thermobiology, University of Lódź, Poland.

出版信息

Biochem Mol Biol Int. 1997 Nov;43(4):883-90. doi: 10.1080/15216549700204691.

DOI:10.1080/15216549700204691
PMID:9385448
Abstract

In the present study, the interactions of imidazoacridinones, C-1311 and C-1371 with human erythrocyte membranes were examined by electron spin resonance spectroscopy (ESR). It was observed that both compounds C-1311 and C-1371 preferentially bind to proteins producing the conformational changes of erythrocyte membrane skeletal proteins.

摘要

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