The effects of imidazoacridinones, new antineoplastic agents, on the human erythrocyte membrane.
作者信息
Jóźwiak Z, Pacholska M, Szwarocka A
机构信息
Department of Thermobiology, University of Lódź, Poland.
出版信息
Biochem Mol Biol Int. 1997 Nov;43(4):883-90. doi: 10.1080/15216549700204691.
PMID:9385448
Abstract
In the present study, the interactions of imidazoacridinones, C-1311 and C-1371 with human erythrocyte membranes were examined by electron spin resonance spectroscopy (ESR). It was observed that both compounds C-1311 and C-1371 preferentially bind to proteins producing the conformational changes of erythrocyte membrane skeletal proteins.
摘要
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