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食管鳞状细胞癌放疗后的吞咽功能

Swallowing performance after radiotherapy for squamous cell carcinoma oesophagus.

作者信息

Rathi A K, Bahadur A K, Broor S L

机构信息

Department of Radiotherapy, L.N.J.P.N and G.B.Pant Hospitals, Maulana Azad Medical College, New Delhi.

出版信息

Trop Gastroenterol. 1997 Jul-Sep;18(3):95-7.

PMID:9385848
Abstract

OBJECTIVE

To consider assessment of swallowing performance status as an alternative to survival in reporting results of treatment in patients with carcinoma oesophagus.

METHODS

Twenty five patients of squamous cell carcinoma of oesophagus treated with radiotherapy were evaluated clinically, radiologically and endoscopically, to assess their response to treatment.

RESULTS

Two months after radiotherapy, 10 of 25 patients had swallowing score-1. During radiotherapy, oesophagitis involving normal oesophagus and diseased segment was seen in 64% of cases. Fifty six percent of patients developed stricture (24% malignant, 32% benign). At the end of two years, only five patients were alive, two with swallowing score of 2, two with swallowing score of 3 and one with swallowing score of 4.

CONCLUSION

As the overall survival in carcinoma oesophagus is poor, the short term criteria for assessing the response of treatment should be swallowing performance status. Radiotherapy treatment can provide substantial palliation for patients debilitated by dysphagia.

摘要

目的

在报告食管癌患者的治疗结果时,考虑将吞咽功能状态评估作为生存情况的替代指标。

方法

对25例接受放疗的食管鳞状细胞癌患者进行临床、放射学和内镜评估,以评估其对治疗的反应。

结果

放疗后两个月,25例患者中有10例吞咽评分为1分。放疗期间,64%的病例出现累及正常食管和病变节段的食管炎。56%的患者出现狭窄(24%为恶性,32%为良性)。两年结束时,仅5例患者存活,2例吞咽评分为2分,2例吞咽评分为3分,1例吞咽评分为4分。

结论

由于食管癌的总体生存率较低,评估治疗反应的短期标准应为吞咽功能状态。放疗可为因吞咽困难而虚弱的患者提供显著的姑息治疗。

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