Schumacher H R
Arthritis Rheum. 1976 May-Jun;19(3):629-36. doi: 10.1002/art.1780190317.
Eight patients with bronchogenic carcinoma presented with painful joint effusions as part of the syndrome of hypertrophic osteoarthropathy. Elevated sedimentation rates and symptomatic relief with aspirin were common, but synovial fluids all had leukocyte counts less than 500/mm3. Synovial microvascular injury was found in all patients, and electron-dense deposits in synovial vessel walls were identified in 5 cases. These vascular deposits suggest a role for circulating materials in pathogenesis.
8例支气管源性癌患者出现关节疼痛性积液，这是肥大性骨关节病综合征的一部分。血沉升高和阿司匹林治疗后症状缓解很常见，但所有滑膜液白细胞计数均低于500/mm³。所有患者均发现滑膜微血管损伤，5例患者滑膜血管壁有电子致密沉积物。这些血管沉积物提示循环物质在发病机制中起作用。
