Brinkmann B, Hernandez M A, Karger B, Ortmann C
Institute of Legal Medicine, University of Münster, Germany.
Int J Legal Med. 1997;110(6):295-8. doi: 10.1007/s004140050091.
Three immunohistochemically different myelomonocytic subtypes, i.e. MRP8, MRP14 and 27E10 were quantitatively evaluated in the intraalveolar, alveolar-interstitial and alveolar-intracapillary lung compartments. Lung sections from 5 major groups with defined causes of death, i.e. drowning and death during immersion (DI), cerebral/intracranial haemorrhages (CH), sudden cardiac deaths (SCD), hanging and throttling (HT) and immediate trauma deaths (ITD) were stained and the positive cells counted. The results show clear differences of the cell numbers on average. Among the different compartments the intracapillary cell count exhibits the highest numbers. If the cell counts are compared to the different causes of death, DI shows the highest values and ITD the lowest. The individual values, however, show considerable variations in all compartments and especially in the low cell count range. Within the DI group two subgroups can be differentiated, one having low and the other one having high cell numbers. This can be due to the type of agony, i.e. drowning versus immersion/hydrocution, or to resuscitation attempts or to a combination of both factors.
对三种免疫组织化学不同的骨髓单核细胞亚型，即MRP8、MRP14和27E10，在肺泡内、肺泡间质和肺泡毛细血管肺区室进行了定量评估。对5个主要死亡原因明确的组别的肺切片进行染色并对阳性细胞计数，这5个组别分别是溺水和浸泡死亡（DI）、脑/颅内出血（CH）、心源性猝死（SCD）、绞刑和扼杀（HT）以及即时创伤死亡（ITD）。结果显示平均细胞数量存在明显差异。在不同的肺区室中，毛细血管内细胞计数最高。如果将细胞计数与不同的死亡原因进行比较，DI组的值最高，ITD组的值最低。然而，各个值在所有肺区室中，尤其是在低细胞计数范围内，都表现出相当大的差异。在DI组内可以区分出两个亚组，一个细胞数量低，另一个细胞数量高。这可能是由于痛苦的类型，即溺水与浸泡/水中窒息，或者是复苏尝试，或者是这两个因素的综合作用。
