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化学涂覆有交联白蛋白的硅橡胶的血液相容性。

Blood compatibility of silicone rubber chemically coated with cross-linked albumin.

作者信息

Guidoin R G, Awad J, Brassard A, Domurado D, Lawny F, Barbotin J N, Calvor C, Broun G

出版信息

Biomater Med Devices Artif Organs. 1976;4(2):205-24. doi: 10.3109/10731197609118651.

DOI:10.3109/10731197609118651
PMID:938712
Abstract

A new method is reported for chemically coating cross-linked albumin onto silicone rubber in an attempt to improve the blood compatibility of the material. Promising results were obtained in an evaluation using both vena cava and renal embolus antithrombogenicity tests ondogs. Coated silicone rubber rings induced much less renal emboli than uncoated ones after one week implantation.

摘要

报道了一种将交联白蛋白化学涂覆在硅橡胶上的新方法,旨在改善该材料的血液相容性。在对狗进行的腔静脉和肾栓子抗血栓形成性测试评估中获得了有希望的结果。植入一周后,涂覆的硅橡胶环引起的肾栓子比未涂覆的少得多。

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