[Soluble interleukin-2 receptor in patients with urinary bladder cancer].

Soluble interleukin-2 receptor (sIL-2R) levels in the serum and the effect of the sIL-2R on the natural killer cell factor (NKCF) activity were studied in 31 patients with transitional cell cancer of the urinary bladder. The results showed that serum levels of sIL-2R in the patients were significantly higher than those of controls. sIL-2R level correlated with the stage of the disease. Furthermore, sIL-2R was able to suppress NKCF activity. The results suggest that the sIL-2R may reflect the status of anti-tumor immunity.