Yan J, Hirotoshi O, Masashhi U
Department of Surgery, Sichuan Cancer Hospital and Institute, Chengdu.
Zhonghua Zhong Liu Za Zhi. 1996 Nov;18(6):451-4.
Five hundred and thirty-three cases (males 346, females 187; average age 58.9) of early colorectal carcinomas including 482 cases with single lesion and 51 cases with synchronous multiple lesions diagnosed at Cancer Institute Hospital in Japan from Jan. 1991 through June. 1995, were analyzed clinicopathologically. Early carcinomas accounted for 45.6% among all colorectal carcinomas. The total number of lesions was 622. Tumors were localized in the sigmoid colon in 42.8% of the 622 lesions and in 22.9% in the rectum. Macroscopically, 31.0% of the tumors were of pedunculated type and 29.3% was of subpedunculated type. With the growth of polyps, the frequency of malignant changes increased. Therefore, polyps should be considered as premalignant lesions and treated early.
对1991年1月至1995年6月期间在日本癌症研究所医院诊断的533例早期结直肠癌（男性346例，女性187例；平均年龄58.9岁）进行了临床病理分析，其中包括482例单发病变和51例同时性多发病变。早期癌占所有结直肠癌的45.6%。病变总数为622个。622个病变中，42.8%的肿瘤位于乙状结肠，22.9%位于直肠。宏观上，31.0%的肿瘤为有蒂型，29.3%为亚蒂型。随着息肉的生长，恶变频率增加。因此，息肉应被视为癌前病变并尽早治疗。
