Yang Y, Zhang C, Chen Z
Department of Physiology, Lanzhou Military Medical College of PLA.
Zhen Ci Yan Jiu. 1996;21(1):45-8.
Arginine vasopressin (AVP) has been shown to have significant effects on the thermoregulation. The present experiments were to investigate the effect of electroacupuncture (EA) on the discharge activity of temperature-sensitive neurons of preoptic-anterior hypothalamus (PO-AH) in rabbits treated by AVP and arginine vasopressin monoclonal antibody (AVPMcAb). The results were as follows: (1) AVP could markedly promote the firing activity of EA on heat-sensitive neurons in PO-AH. (2) AVPMcAb could markedly reduce the effect of EA on temperature-sensitive neurons in PO-AH. Experimental results indicated that the mechanisms of EA on hypothermia might be related to AVP.
精氨酸加压素（AVP）已被证明对体温调节有显著影响。本实验旨在研究电针（EA）对经AVP和精氨酸加压素单克隆抗体（AVPMcAb）处理的家兔视前区-下丘脑前部（PO-AH）温度敏感神经元放电活动的影响。结果如下：（1）AVP可显著促进EA对PO-AH中热敏神经元的放电活动。（2）AVPMcAb可显著降低EA对PO-AH中温度敏感神经元的作用。实验结果表明，EA致体温降低的机制可能与AVP有关。
