Chen B, Xu C, Tian Y
Department of Cardiology, People's Hospital, Beijing Medical University.
Zhonghua Nei Ke Za Zhi. 1996 Apr;35(4):239-41.
The clinical data of 100 female cases with suspected coronary heart disease (CHD) undergoing coronary artery angiography (CAA) were analysed. CHD was defined as an estimated diameter stenosis of 75% and more in the main coronary arteries or coronary stenosis of 50%-75% with evidence of cardiac ischemia. Forty-eight case were confirmed as having CHD by CAA. The remaining 52 cases were confirmed as non-CHD and served as the control group, including 49 cases with normal coronary arteries and 3 cases with stenosis of less than 50% in the right coronary artery or left anterior descending artery. The risk factors of CHD and clinical characteristics of chest pain were compared for the two groups. The data demonstrated that menopause was a special risk factor for females and the incidence of CHD was increasing with aging after menopause. However, the clinical characteristics of chest pain in female CHD were usually atypical. When chest pain, whether clinically typical or atypical, were present after menopause and accompanied by evident risk factors, the probability of CHD would be high. If there was only chest pain without any risk factor after menopause, the diagnosis of CHD would be less likely.
对100例疑似冠心病（CHD）且接受冠状动脉造影（CAA）的女性患者的临床资料进行了分析。冠心病定义为主要冠状动脉估计直径狭窄75%及以上，或冠状动脉狭窄50%-75%且有心脏缺血证据。48例经CAA确诊为冠心病。其余52例确诊为非冠心病，作为对照组，包括49例冠状动脉正常和3例右冠状动脉或左前降支狭窄小于50%的患者。比较了两组冠心病的危险因素和胸痛的临床特征。数据表明，绝经是女性的一个特殊危险因素，绝经后冠心病发病率随年龄增长而增加。然而，女性冠心病患者胸痛的临床特征通常不典型。绝经后出现胸痛，无论临床上典型与否，且伴有明显危险因素时，患冠心病的可能性较高。如果绝经后仅有胸痛而无任何危险因素，则冠心病的诊断可能性较小。
