Pan M, Suárez de Lezo J, Medina A, Romero M, Hernández E, Segura J, Melian F, Wangüemert F, Landin M, Benítez F, Amat M, Velasco F, Torres A
Hospital Reina Sofía, University of Córdoba, Spain.
Am J Cardiol. 1997 Nov 15;80(10):1336-8. doi: 10.1016/s0002-9149(97)00676-0.
Two hundred twenty-eight patients with successful coronary stent implantation were randomized either to protamine administration and femoral sheath removal (group I, n = 117) or no heparin neutralization and delayed sheath removal (group II, n = 111). The hospital stay after treatment was shorter in patients receiving protamine; therefore, protamine use for neutralizing circulating heparin may be safely administered immediately after stent implantation.
228例成功植入冠状动脉支架的患者被随机分为两组，一组接受鱼精蛋白注射并拔除股动脉鞘管（I组，n = 117），另一组不进行肝素中和且延迟拔除鞘管（II组，n = 111）。接受鱼精蛋白治疗的患者治疗后的住院时间较短；因此，在支架植入后可立即安全地使用鱼精蛋白来中和循环中的肝素。
