[丝裂霉素CS-碘油动脉灌注化疗治疗肝细胞癌：灌注方法的评估]
[Arterial infusion chemotherapy with SMAN CS-Lipiodol for hepatocellular carcinoma evaluation of infusion method].
作者信息
Takizawa K, Obuchi M, Honda M, Matsuoka S, Shima H, Uchiyama K, Hasebe S, Doai K, Satoh S, Kuniyasu Y
机构信息
Dept. of Radiology, Fujigaoka Hospital, Showa University.
出版信息
Gan To Kagaku Ryoho. 1997 Nov;24(14):2117-22.
Forty-four patients with hepatocellular carcinoma were treated with oily anticancer agent SMANCS dissolved in Lipiodol (SMANCS-LPD). The local response rate after the first arterial infusion in all patients was 39%, against 63% in 27 patients with Lipiodol accumulation occupying more than two third of tumor areas. Repeated arterial infusion of SMANCS-LPD did not enhance the therapeutic effect. An infusion of 4mg of SMANCS was ineffective for patients with tumors distributing in bilateral lobes of liver, and 6 mg was recommended for such cases.
44例肝细胞癌患者接受了溶解于碘油（SMANCS-LPD）中的油性抗癌剂SMANCS治疗。所有患者首次动脉灌注后的局部缓解率为39%，而在27例碘油积聚占据肿瘤面积超过三分之二的患者中，该缓解率为63%。重复动脉灌注SMANCS-LPD并未增强治疗效果。对于肿瘤分布于肝双侧叶的患者，4mg的SMANCS灌注无效，此类病例建议使用6mg。
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