The lineage commitment of haemopoietic progenitor cells.

作者信息

Cross M A, Enver T

机构信息

Department of Experimental Haematology, Paterson Institute for Cancer Research, Christie Hospital National Health Service Trust, Manchester, UK.

出版信息

Curr Opin Genet Dev. 1997 Oct;7(5):609-13. doi: 10.1016/s0959-437x(97)80007-x.

Multipotent haemopoietic progenitor cells appear to be 'primed' for commitment by co-expression of a multiplicity of genes characteristic of different lineages. Lineage commitment proceeds as the consolidation of a distinct pattern of gene expression out of this milieu.