Morio B, Ritz P, Verdier E, Montaurier C, Beaufrere B, Vermorel M
CRNH, Université d'Auvergne, Laboratoire de Nutrition Humaine, Clermont-Ferrand, France.
Br J Nutr. 1997 Nov;78(5):709-22. doi: 10.1079/bjn19970189.
The aim of the present study was to validate against the doubly-labelled water (DLW) technique the factorial method and the heart rate (HR) recording method for determining daily energy expenditure (DEE) of elderly people in free-living conditions. The two methods were first calibrated and validated in twelve healthy subjects (six males and six females; 70.1 (SD 2.7) years) from open-circuit whole-body indirect calorimetry measurements during three consecutive days and during 1 d respectively. Mean energy costs of the various usual activities were determined for each subject using the factorial method, and individual relationships were set up between HR and energy expenditure for the HR recording method. In free-living conditions, DEE was determined over the same period of time by the DLW, the factorial and the HR recording methods during 17, 14 and 4 d respectively. Mean free-living DEE values for men estimated using the DLW, the factorial and the HR recording methods were 12.8 (SD 3.1), 12.7 (SD 2.2) and 13.5 (SD 2.7) MJ/d respectively. Mean free-living DEE values for women were 9.6 (SD 0.8), 8.8 (SD 1.2) and 10.2 (SD 1.5) MJ/d respectively. No significant differences were found between the three methods for either sex, using the Bland & Altman (1986) test. Mean differences in DEE of men were -0.9 (SD 11.8) % between the factorial and DLW methods, and + 4.7 (SD 16.1) % between the HR recording and DLW methods. Similarly, in women, mean differences were -7.7 (SD 12.7) % between the factorial and DLW methods, and + 5.9 (SD 8.8) % between the HR recording and DLW methods. It was concluded that the factorial and the HR recording methods are satisfactory alternatives to the DLW method when considering the mean DEE of a group of subjects. Furthermore, mean energy costs of activities calculated in the present study using the factorial method were shown to be suitable for determining free-living DEE of elderly people when the reference value (i.e. sleeping metabolic rate) is accurately measured.
本研究的目的是针对双标记水(DLW)技术,验证用于确定老年人在自由生活条件下每日能量消耗(DEE)的因子法和心率(HR)记录法。这两种方法首先在12名健康受试者(6名男性和6名女性;年龄70.1(标准差2.7)岁)中进行校准和验证,分别在连续三天和1天内通过开路式全身间接量热法测量。使用因子法为每个受试者确定各种日常活动的平均能量消耗,并为HR记录法建立HR与能量消耗之间的个体关系。在自由生活条件下,分别通过DLW、因子法和HR记录法在17天、14天和4天内确定同一时间段的DEE。使用DLW、因子法和HR记录法估计的男性自由生活DEE平均值分别为12.8(标准差3.1)、12.7(标准差2.2)和13.5(标准差2.7)MJ/天。女性自由生活DEE平均值分别为9.6(标准差0.8)、8.8(标准差1.2)和10.2(标准差1.5)MJ/天。使用Bland & Altman(1986)检验,发现三种方法在男女两性中均无显著差异。男性DEE在因子法和DLW法之间的平均差异为-0.9(标准差11.8)%,在HR记录法和DLW法之间为+4.7(标准差16.1)%。同样,在女性中,因子法和DLW法之间的平均差异为-7.7(标准差12.7)%,HR记录法和DLW法之间为+5.9(标准差8.8)%。得出的结论是,在考虑一组受试者的平均DEE时,因子法和HR记录法是DLW法令人满意的替代方法。此外,如果准确测量参考值(即睡眠代谢率),本研究中使用因子法计算的活动平均能量消耗适用于确定老年人的自由生活DEE。