迈向用于代谢工程的虚拟实验室系统：生化工程系统分析工具包（BEST-KIT）的开发。

Toward a virtual-labo-system for metabolic engineering: development of biochemical engineering system analyzing tool-kit (BEST-KIT).

作者信息

Okamoto M, Morita Y, Tominaga D, Tanaka K, Kinoshita N, Ueno J I, Miura Y, Maki Y, Eguchi Y

机构信息

Department of Biochemical Engineering and Science, Kyushu Institute of Technology, Fukuoka, Japan.

出版信息

Pac Symp Biocomput. 1997:304-15.

PMID:9390301

Abstract

BEST-KIT is an efficient and user-friendly "biochemical engineering system analyzing tool-kit" integrated the following key modules: 1) mathematical modeling and editing of reaction-scheme, 2) automatic derivation of differential equations, 3) numerical calculation, 4) nonlinear optimization, 5) visualization, 6) retrieve the information on reaction mechanism and kinetic parameters from data-base of metabolic pathways. The users of this simulator are assumed to be unfamiliar with computer technology and with computer programming. The integrated interface (UNIX version) is based on Xlib, XToolkit and OSF/Motif Widget.

摘要

BEST-KIT是一个高效且用户友好的“生化工程系统分析工具包”，集成了以下关键模块：1）反应方案的数学建模与编辑；2）微分方程的自动推导；3）数值计算；4）非线性优化；5）可视化；6）从代谢途径数据库中检索反应机制和动力学参数的信息。假定该模拟器的用户不熟悉计算机技术和计算机编程。集成界面（UNIX版本）基于Xlib、XToolkit和OSF/Motif Widget。