Esu-Williams E, Mulanga-Kabeya C, Takena H, Zwandor A, Aminu K, Adamu I, Yetunde O, Akinsete I, Patrel D, Peeters M, Delaporte E
HIV Screening Centre, University of Calabar, Nigeria.
J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Nov 1;16(3):204-10. doi: 10.1097/00042560-199711010-00010.
To determine current data on HIV infection and to further confirm the presence of HIV-1 group O infection in Nigeria, 2300 samples from five states were tested for the presence of HIV antibody. A convenience sampling was obtained from pregnant women, tuberculosis (TB) patients, commercial sex workers (CSWs), blood donors, patients with sexually transmitted diseases (STDs), patients with skin diseases, male clients of CSWs, outpatients suspected to have AIDS, truck drivers, and community dwellers. With the exception of pregnant women, the HIV prevalences in all these groups were high: 60.6% in CSWs, 16.2% in TB patients, 7.7% in blood donors in some states, and 16% in the rural area of Kano State. Male clients of CSWs, truck drivers, and STD patients had prevalences of 7.8%, 8.6%, and 21.2%, respectively. Regional differences in relation to HIV prevalences were observed; HIV-2 and most of the HIV-1/2 infections were found in the southern states of Nigeria. Higher HIV prevalences were observed in the north-northeast in pregnant women, TB patients, and CSWs, but for blood donors, higher rates were seen in the southeast-southwest. One asymptomatic 50-year-old woman, a community dweller in Kano, was identified to be HIV-1 group O-positive. Compared with data from national surveillance studies in 1991/1992 and 1993/1994, a substantial increase in HIV infection was observed. Our results show a growing incidence of HIV infection in Nigeria and suggest the presence of a rural HIV epidemic. The identification of HIV-1 group O in Kano shows that this virus strain is geographically widespread in Nigeria.
为了确定有关艾滋病毒感染的现有数据，并进一步证实尼日利亚存在艾滋病毒-1型O组感染，对来自五个州的2300份样本进行了艾滋病毒抗体检测。通过便利抽样从孕妇、结核病患者、商业性工作者、献血者、性传播疾病患者、皮肤病患者、商业性工作者的男性客户、疑似患有艾滋病的门诊患者、卡车司机和社区居民中获取样本。除孕妇外，所有这些群体中的艾滋病毒流行率都很高：商业性工作者中为60.6%，结核病患者中为16.2%，某些州的献血者中为7.7%，卡诺州农村地区为16%。商业性工作者的男性客户、卡车司机和性传播疾病患者的流行率分别为7.8%、8.6%和21.2%。观察到艾滋病毒流行率的区域差异；在尼日利亚南部各州发现了艾滋病毒-2型以及大多数艾滋病毒-1/2型感染。在孕妇、结核病患者和商业性工作者中，东北部的艾滋病毒流行率较高，但对于献血者，东南部-西南部的流行率较高。一名来自卡诺的50岁无症状社区女性被确定为艾滋病毒-1型O组阳性。与1991/1992年和1993/1994年全国监测研究的数据相比，观察到艾滋病毒感染大幅增加。我们的结果显示尼日利亚艾滋病毒感染发病率不断上升，并表明农村地区存在艾滋病毒疫情。在卡诺发现艾滋病毒-1型O组表明该病毒株在尼日利亚广泛分布于各地。
