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慢性胰腺炎所致慢性疼痛的外科治疗

Surgical management of chronic pain from chronic pancreatitis.

作者信息

McHale A, Buechter K J, Cohn I, O'Leary J P

机构信息

Department of Surgery, Louisiana State University Medical Center, New Orleans 70112, USA.

出版信息

Am Surg. 1997 Dec;63(12):1119-22; discussion 1122-3.

PMID:9393263
Abstract

Chronic pain from chronic pancreatitis remains a difficult clinical problem. We present the results of surgical attempts to control this pain. For the past 3 years, all patients with chronic pancreatitis and pain requiring high-dose narcotics or hospitalization for pain control were evaluated by the following algorithm. Any anatomic pathology causing ductal dilatation was surgically addressed first (Puestow's procedure, pseudocyst drainage, or sphincteroplasty). If there was no evidence of ductal dilatation, or if pain recurred postoperatively, denervation procedures were performed (splenopancreatic flap, thorascopic sympathectomy, or resection). Pain recurrence was defined as the need for further hospitalization or reoperation. Data were analyzed by comparison of two proportions. Follow-up averaged 26 months. Thirty-seven patients underwent 44 operations solely in an attempt to control pain; 62 per cent were male, and 70 per cent had chronic alcoholic pancreatitis. Our results show that surgical management provides relief in 68 per cent of patients, and no one procedure is clearly superior to others.

摘要

慢性胰腺炎所致的慢性疼痛仍是一个棘手的临床问题。我们展示了为控制这种疼痛而进行手术尝试的结果。在过去3年中,所有患有慢性胰腺炎且疼痛需要大剂量麻醉药或因疼痛控制而住院的患者,均按以下流程进行评估。任何导致导管扩张的解剖学病变首先通过手术处理(普埃斯托手术、假性囊肿引流或括约肌成形术)。如果没有导管扩张的证据,或者疼痛在术后复发,则进行去神经手术(脾胰瓣手术、胸腔镜交感神经切除术或切除术)。疼痛复发定义为需要进一步住院或再次手术。通过比较两个比例对数据进行分析。平均随访26个月。37例患者仅为控制疼痛接受了44次手术;62%为男性,70%患有慢性酒精性胰腺炎。我们的结果表明,手术治疗使68%的患者疼痛得到缓解,且没有一种手术方法明显优于其他方法。

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