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慢性胰腺炎患者假性囊肿的手术治疗。

Operative treatment of pseudocysts in patients with chronic pancreatitis.

作者信息

Usatoff V, Brancatisano R, Williamson R C

机构信息

Department of Surgery, Hammersmith Hospital, Imperial College School of Medicine, London, UK.

出版信息

Br J Surg. 2000 Nov;87(11):1494-9. doi: 10.1046/j.1365-2168.2000.01560.x.

Abstract

BACKGROUND

Pseudocysts associated with chronic pancreatitis are generally intrapancreatic and associated with parenchymal disease. They tend to persist and cause complications. Minimally invasive methods of treatment challenge the traditional techniques of operative management. Surgical operation allows definitive treatment of the pseudocyst with the option of dealing appropriately with the diseased pancreas and excluding a neoplastic process. The aim of this study was to review the safety and efficacy of a surgical approach to the management of pseudocysts associated with chronic pancreatitis.

METHODS

A personal series of 112 consecutive patients operated for pseudocysts in the setting of chronic pancreatitis was reviewed. Chronic pancreatitis was confirmed by imaging studies in association with exocrine and/or endocrine failure. Cysts were multiple in 31 patients and presented with complications other than pain in 47. Data were collected prospectively regarding the clinical presentation, the nature of the operation and its outcome.

RESULTS

Forty-eight patients (43 per cent) underwent drainage procedures, 56 (50 per cent) had a resection and eight (7 per cent) had a combination. Larger cysts and those located in the head and neck tended to be drained, while smaller and distal cysts were more often resected. The morbidity rate was 28 per cent and the operative mortality rate was 1 per cent. The cyst recurrence rate was 3 per cent and pain was relieved in 74 per cent of patients.

CONCLUSION

Operative management of pseudocysts associated with chronic pancreatitis is effective with low morbidity and mortality rates. The introduction of newer minimally invasive techniques will have to withstand comparison to this traditional approach.

摘要

背景

与慢性胰腺炎相关的假性囊肿通常位于胰腺内,并与实质疾病相关。它们往往持续存在并引发并发症。微创治疗方法对传统的手术管理技术构成了挑战。外科手术能够对假性囊肿进行确定性治疗,同时可选择适当处理病变胰腺并排除肿瘤性病变。本研究的目的是回顾一种手术方法治疗与慢性胰腺炎相关假性囊肿的安全性和有效性。

方法

回顾了本人连续收治的112例因慢性胰腺炎相关假性囊肿接受手术的患者。通过影像学检查结合外分泌和/或内分泌功能衰竭确诊为慢性胰腺炎。31例患者的囊肿为多发,47例出现除疼痛以外的并发症。前瞻性收集有关临床表现、手术性质及其结果的数据。

结果

48例患者(43%)接受了引流手术,56例(50%)进行了切除术,8例(7%)采用了联合手术。较大的囊肿以及位于胰头和颈部的囊肿倾向于进行引流,而较小的远端囊肿更常进行切除。发病率为28%,手术死亡率为1%。囊肿复发率为3%,74%的患者疼痛得到缓解。

结论

手术治疗与慢性胰腺炎相关的假性囊肿有效,发病率和死亡率较低。引入更新的微创技术必须经得起与这种传统方法的比较。

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