de Kort L M, Nesselaar C H, van Gool J D, de Jong T P
Paediatric Renal Centre, University Hospital for Children and Youth, University of Utrecht, The Netherlands.
Br J Urol. 1997 Nov;80(5):731-3. doi: 10.1046/j.1464-410x.1997.00435.x.
To evaluate whether colonic enema irrigation influences the urodynamic characteristics of patients with spina bifida, an overactive bladder and detrusor sphincter dyssynergia (DSD).
Since 1991, 83 patients with spina bifida at our institution have treated their bowel dysfunction by colonic irrigation every 24-48 h. In 12 patients (seven boys and five girls, mean age 7.7 years, range 0.7-13.8) with an overactive bladder and DSD, urodynamic studies of the bladder before and after enema treatment were available with no intercurrent changes in urological therapy.
There were no significant changes overall in bladder capacity, leak-point pressure, bladder compliance and bladder instability in the selected group of children.
Although enema therapy for bowel treatment in patients with spina bifida gave good results for faecal incontinence, with good patient compliance, no favourable effect on bladder function should be expected in most patients with a high-risk urinary tract dysfunction. Further study is needed to determine factors in patients who will benefit urologically from enema treatment.
评估结肠灌肠冲洗是否会影响患有脊柱裂、膀胱过度活动症和逼尿肌括约肌协同失调(DSD)患者的尿动力学特征。
自1991年以来,我院83例脊柱裂患者每24 - 48小时通过结肠灌洗治疗肠道功能障碍。在12例患有膀胱过度活动症和DSD的患者(7名男孩和5名女孩,平均年龄7.7岁,范围0.7 - 13.8岁)中,可获得灌肠治疗前后膀胱的尿动力学研究结果,且泌尿外科治疗无并发变化。
在所选儿童组中,膀胱容量、漏点压力、膀胱顺应性和膀胱不稳定总体上无显著变化。
尽管脊柱裂患者的灌肠疗法对肠道治疗在大便失禁方面取得了良好效果,且患者依从性良好,但对于大多数有高风险尿路功能障碍的患者,预计对膀胱功能无有利影响。需要进一步研究以确定能从灌肠治疗中在泌尿外科方面获益的患者因素。