Koskinen S K, Ylä-Outinen H, Aho H J, Komu M E
Department of Diagnostic Radiology, Turku University Hospital, University of Turku, Finland.
Acta Radiol. 1997 Nov;38(6):1071-5. doi: 10.1080/02841859709172133.
To investigate magnetization transfer (MT) parameters and rotating frame relaxation time T1 rho in patellar cartilage at different levels of degeneration.
Thirty cadaveric patellae were examined at 0.1 T using the time-dependent saturation-transfer MT technique and the spin lock (SL) technique. In an SL experiment, nuclear spins are locked with a radiofrequency (RF) field, and the locked nuclear magnetization relaxes along the magnetic component of the locking RF field. The specimens were divided into three groups according to the level of cartilage degeneration. MT parameters and T1 rho were measured.
The MT effect was greater in degenerated cartilage than in normal cartilage. T1 rho was longer in advanced cartilage degeneration than in intermediate cartilage degeneration.
The results suggest that more studies are needed to fully establish the value of SL imaging in cartilage degeneration.
研究不同退变程度的髌软骨的磁化传递(MT)参数及旋转框架弛豫时间T1ρ。
使用时间依赖饱和转移MT技术和自旋锁定(SL)技术,在0.1T磁场下对30个尸体髌骨进行检查。在SL实验中,核自旋被射频(RF)场锁定,锁定的核磁化沿着锁定RF场的磁分量弛豫。根据软骨退变程度将标本分为三组,测量MT参数和T1ρ。
退变软骨的MT效应大于正常软骨。晚期软骨退变的T1ρ长于中期软骨退变。
结果表明,需要更多研究来全面确定SL成像在软骨退变中的价值。