Gene dosage effect in human triploid fibroblasts.
作者信息
Junien C, Rubinson H, Dreyfus J C, Meinenhofer M C, Ravise N, Boué J, Boué A
出版信息
Hum Genet. 1976 Jul 7;33(1):61-6. doi: 10.1007/BF00447287.
PMID:939558
Abstract
The activity of 13 cytoplasmic enzymes has been determined in fibroblast extracts from 9 triploid and 13 control lines. The results show a high activity for 2 X-linked enzymes, glucose 6-phosphate dehydrogenase and phosphoglycerate kinase. These data, together with cytogenetic observations, support the contention that 2 X chromosomes were active in the triploid lines.
摘要
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