胃底腺息肉：另外三例病例报告提示可能与抑酸治疗有关。

Fundic gland polyps: three other case reports suggesting a possible association with acid suppressing therapy.

作者信息

Van Vlierberghe H, De Vos M, De Cock G, Cuvelier C, Elewaut A

机构信息

University Hospital, Department of Gastroenterology, Ghent, Belgium.

出版信息

Acta Gastroenterol Belg. 1997 Jul-Sep;60(3):240-2.

PMID:9396183

Abstract

We describe three patients who developed fundic gland polyps after starting a treatment with acid suppressive agents. All three patients were treated for a long time with H2-blockers or proton pump inhibiting agents for reflux oesophagitis. In one patient the fundic gland polyps disappeared after discontinuation of the acid suppressing therapy. A possible causal role of these agents is suggested. A review of the literature about fundic gland polyps and their possible association with acid suppressive therapy and a short review about proton pump inhibiting agents and the appearance of gastric polyps in general is given.

摘要

我们描述了三名患者，他们在开始使用抑酸剂治疗后出现了胃底腺息肉。所有三名患者均长期使用H2受体阻滞剂或质子泵抑制剂治疗反流性食管炎。其中一名患者在停止抑酸治疗后胃底腺息肉消失。提示了这些药物可能的因果作用。本文对有关胃底腺息肉及其与抑酸治疗可能关联的文献进行了综述，并对质子泵抑制剂及一般胃息肉的出现进行了简要综述。