Kim Jin-Soo, Chae Hiun Suk, Kim Hyung-Keun, Cho Young-Seok, Park Yong-Wan, Son Hye-Suk, Han Sok-Won, Choi Kyu-Yong
Department of Internal Medicine, College of Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2008 May;51(5):305-8.
Fundic gland polyps (FGPs) are the most common type of gastric polyps, found primarily in the fundus and body of stomach. Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts. We experienced a patient who showed spontaneous resolution of multiple FGPs after the cessation of omeprazole. Two years ago, the patient showed only endoscopically confirmed erosive esophagitis without FGPs. Multiple FGPs developed one year after the use of omeprazole and spontaneously disappeared with the cessation of omeprazole.
胃底腺息肉（FGPs）是最常见的胃息肉类型，主要见于胃底和胃体。长期使用质子泵抑制剂（PPI）已知与正常胃黏膜的某些组织学改变有关，包括壁细胞增生和胃底腺囊肿。我们遇到一名患者，在停用奥美拉唑后，其多个胃底腺息肉出现了自发消退。两年前，该患者内镜检查仅确诊为糜烂性食管炎，无胃底腺息肉。使用奥美拉唑一年后出现多个胃底腺息肉，停用奥美拉唑后息肉自发消失。
