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欧洲女性使用激素替代疗法(HRT)的跨国研究。

Cross-national study of women's use of hormone replacement therapy (HRT) in Europe.

作者信息

Schneider H P

机构信息

Department of Obstetrics and Gynecology, University of Münster, Germany.

出版信息

Int J Fertil Womens Med. 1997;42 Suppl 2:365-75.

PMID:9397384
Abstract

The benefits of hormone replacement therapy (HRT) to perimenopausal and postmenopausal women are well established. Women from France, Germany, Spain, and the United Kingdom were interviewed to determine: (1) knowledge and views of menopause and HRT; (2) history of HRT among current and lapsed users; and (3) reasons of non-users for never having taken HRT. In 1996, nearly 1,500 women aged 40 to 65 answered a short series of questions concerning menopause and HRT as part of a consumer omnibus survey; others (n = 929) participated in a focused survey of attitudes toward and use of HRT. Only one-third of perimenopausal and 13% of postmenopausal women currently were taking HRT. About 25% of postmenopausal women reported having taken HRT at some time. The proportion of perimenopausal women using HRT varied by country, and ranged from 18% in Spain to 55% in France. Importantly, about half (range across countries, 38% to 61%) of the women interviewed had not discussed menopause or its symptoms with their doctors. While levels of HRT knowledge varied by country, two-thirds of respondents overall believed they needed more information about HRT. Decisions about beginning HRT and choosing a formulation were viewed by most women as matters of personal choice, to be made with advice from a physician. In summary, despite the benefits of HRT and available choices among drug delivery options, a fairly small proportion of European women use it, largely because most remain poorly informed about the therapy. Increased physician-patient communication and public education programs are needed to provide women with the information they need to make judicious decisions concerning HRT.

摘要

激素替代疗法(HRT)对围绝经期和绝经后女性的益处已得到充分证实。对来自法国、德国、西班牙和英国的女性进行了访谈,以确定:(1)对更年期和HRT的了解与看法;(2)当前使用者和已停用者的HRT使用史;(3)未使用者从未接受HRT的原因。1996年,近1500名40至65岁的女性回答了一系列有关更年期和HRT的简短问题,作为消费者综合调查的一部分;其他929人参与了一项关于对HRT的态度和使用情况的专项调查。目前,只有三分之一的围绝经期女性和13%的绝经后女性在接受HRT治疗。约25%的绝经后女性报告曾在某个时期接受过HRT治疗。使用HRT的围绝经期女性比例因国家而异,从西班牙的18%到法国的55%不等。重要的是,约一半(各国范围为38%至61%)接受访谈的女性未与医生讨论过更年期或其症状。虽然各国对HRT的了解程度有所不同,但总体而言,三分之二的受访者认为她们需要更多关于HRT的信息。大多数女性认为,开始使用HRT和选择药物剂型的决定是个人选择问题,需要在医生的建议下做出。总之,尽管HRT有诸多益处,且在药物递送方式上有多种选择,但使用它的欧洲女性比例相当小,主要原因是大多数女性对该疗法的了解仍然很少。需要加强医患沟通并开展公众教育项目,为女性提供做出关于HRT的明智决定所需的信息。

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