Kay M A, Liu D, Hoogerbrugge P M
Department of Medicine, University of Washington, Seattle 98195, USA.
Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12744-6. doi: 10.1073/pnas.94.24.12744.
In recent years, there have been a number of technological breakthroughs that have allowed for clinical trials in gene therapy to be initiated. In combination with the genome initiative, the potential for new therapeutics is limitless. Although an enormous amount of information has been obtained in a relatively short period of time, gene therapy is not yet ready for wide-scale practice. Some of the successes and obstacles that remain are summarized in this report.
近年来,出现了许多技术突破,使得基因治疗的临床试验得以启动。与基因组计划相结合,新疗法的潜力是无限的。尽管在相对较短的时间内已经获得了大量信息,但基因治疗尚未准备好大规模应用。本报告总结了一些已取得的成功和仍然存在的障碍。