Maggioni F, Alessi C, Maggino T, Zanchin G
Department of Neurology and Psychiatric Sciences, University of Padova, Italy.
Cephalalgia. 1997 Nov;17(7):765-9. doi: 10.1046/j.1468-2982.1997.1707765.x.
A questionnaire was submitted to 430 women 3 days after delivery, asking mainly about features of headache before and during pregnancy, and their possible modification or recurrence; moreover, delivery modalities and the condition of the newborn were evaluated. One-hundred-and-twenty-six (29.3%) were found to be primary headache sufferers (IHS criteria, 1988), 81 of whom had migraine without aura (MO), 12 migraine with aura (MA), and 33 tension-type headache (TH). In all three groups, about 80% showed complete remission or a higher than 50% decrease in the number of attacks. The improvement was more evident after the end of the first trimester; this trend was common to the three primary headaches considered. In our series of primary headaches, there was only one case (MO) which began during pregnancy. In a subgroup of pluripara, headache maintained the improvement presented in the first pregnancy also during the following gravidic periods in about 50% of cases, whereas in the remaining 50% a worsening in parallel with successive pregnancies was found. Primary headaches "per se" do not seem to increase the pregnancy or delivery risks, nor the vitality of the newborn. During pregnancy, drug use was very much reduced and was restricted to a limited number of compounds.
在产后3天，向430名女性发放了一份问卷，主要询问孕前和孕期头痛的特征以及其可能的改善或复发情况；此外，还评估了分娩方式和新生儿状况。发现126名（29.3%）为原发性头痛患者（国际头痛协会标准，1988年），其中81名有无先兆偏头痛（MO），12名有先兆偏头痛（MA），33名有紧张型头痛（TH）。在所有三组中，约80%的患者发作次数完全缓解或减少超过50%。在孕早期结束后改善更为明显；这一趋势在三种原发性头痛中都很常见。在我们的原发性头痛系列中，只有1例（MO）在孕期开始。在经产妇亚组中，约50%的病例在后续孕期中头痛仍保持首次怀孕时的改善情况，而其余50%的病例则发现随着连续怀孕病情恶化。原发性头痛“本身”似乎不会增加妊娠或分娩风险，也不会影响新生儿的活力。在孕期，药物使用大幅减少，仅限于少数几种药物。
